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KMID : 0614619930250010168
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Korean Journal of Gastroenterology
1993 Volume.25 No. 1 p.168 ~ p.175
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Identification and Quantification of Intrahepatic Calculi by Infrared Absorption Spectroscopy
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김영호
김용태/윤용범/최규완/김정룡
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Abstract
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Intrahepatic calculi are stones involving the right and left hepatic ducts. and their branches, peripheral to their junction at the hepatic hilum. The incidence of intrahepatic calculi is high throughout East Asia including Korea compaired with
the
West
and the composition of intrahepatic calculi are different from each other in the different geographic areas. Therefore the analysis for the composition of intrahepatic calculi is important to understand the pathophysiology of intrahepatic
calculi.
However, there is no available data regarding the composition of intrahepatic calculi in Korea. So, we analyzed the compositions of 49 intrahepatic calculi removed through the T-tubes or PTBD tubes by infrared absorption spectroscopy.
The principal component of intrahepatic calculi was calcium bilirubinate (48.1%), followed by calcium palmitate (12.5%) and cholesterol (11.1%). Neither calcium carbonate or calcium phosphate was tound. The 28.5% of dry weight was not analyzed by
infrared absorption spectroscopy Among the 49 cases, 46 cases were pigment stones and 3 cases were cholesterol stones. By the analysis of the principal component, 45 cases were calcium bilirubinate stones. 3 cases were cholesterol stones and 1
case
was
a calcium palmitate stone.
In conclusion, the major type of intrahepatic calculi in Korea is calcium bilirubinate stone and the presence of cholesterol stones sugested the possibility of dissolution therapy for intrahepatic calculi. Further studies for the unmeasured
portion
may
be required to understand the nature of intrahepatic calculi.
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